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KMID : 0357220030150010009
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Journal of Korean Society Physical Therapy
2003 Volume.15 No. 1 p.9 ~ p.25
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An Immunohistochemical Study of Effects of Therapeutic Ultrasound on the Expression of Substance-P in Muscle Contusion Injury
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김용수
김석범/김진상/박래준
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Abstract
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The purpose of this study was to evaluate the effect of therapeutic ultrasound after muscle contusion injury by observed immunoreactivity of substance-P that plays an important role in pain transmission. Ultrasound irradiation(1MHz, 1W/$cm^{2}$ continuous mode, treatment time 5 min) was applied through water submersion technique to 1 limb daily by kept off 5cm from muscle belly of gastrocnemius. The result of this study were as follows. 1. The substance-P was expressed in lamina I and II of dorsal horn of spinal cord, also in lamina IV and around of central cannel of spinal cord. Experimental group was lower expressed than control group with the exception of 1 days. 2. The substance-P immunoreactivity was decreased for 5 days together in lumbar and sacral region of all groups, expecially experimental group was rapidly. These data suggest therapeutic ultrasound may stimulate pain relief by diminish of substance-P in dorsal horn of spinal cord.
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KEYWORD
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